Tuesday, May 17, 2011

Cranberries for Health!



Cranberry Demonstrates
Heart Health Benefits Reported
From Important New Study

Polyphenol-rich cranberry juice may boost
heart health by helping alleviate stiffness of
the arteries, reports an
important new study
from the Boston and Tufts Universities.
High concentrate Cranberry containing 835 milligrams
of total polyphenols and 94 mg of anthocyanins was
associated withimprovements in a measure of arterial
stiffness known as Carotid Femoral Pulse Wave
Velocity, according tofindings published in the
American Journal of Clinical Nutrition.
The research scientists report no benefits were
observed from cranberry juice consumption for other
measures of vascular or cardiovascular function,
including blood pressure or brachial artery flow-
mediated dilation; This measures endothelial
dysfunction... A low value is indicative of a blood
vessel's inability torelax.
"We did observe a highly significant effect of
cranberry juice on stiffness of the central aorta, which
isincreasingly recognized as an important measure of
vascular function with relevance to cardiovascular
disease," wrote the Boston University researchers.
"Overall, our results may provide further support for
the American Heart Association recommendation that
cardiovascular disease risk may be reduced by a diet
rich in vegetables and fruit including cranberries," they
added.
Established and Emerging Health Benefits
of Cranberries
Cranberry is well known for its ability to fight urinary
tract infections. Currently, nearly onethird of parents
in the US give Cranberry juice to their children,
according to a recent statistics.
In 2004, France became the first country to approve a
specific health claim for the North American cranberry
species (Vaccinium macrocarpon) which states that it
can "help reduce the adhesion of certain E.coli bacteria
to the urinary tract walls."
Other health conditions that may benefit from cranberry
include stomach health, with numerous reports indicating
that the berry's natural constituents may inhibit the
adhesion of Helicobacter pylori in the stomach.H. pylori
is the bacteria known to cause peptic ulcers and gastritis.
In addition studies have suggested that proanthocyanidin-
rich cranberry extracts may inhibit the growth and
spread of human oesophageal adenocarcinoma (a cancer
in glandular tissue), or may prevent colon cancervia an
anti-inflammatory mechanism.
For the Boston-based study, he researchers performed
two studies: The first was an acute pilot study with no
placebo involving 15 participants; the second was a
chronic placebo-controlled crossover study with 44
participants with coronary artery disease.
In the acute, non-placebo controlled, pilot study, the
researchers reported that cranberry juice (480 mL) was
associated with improvements in both brachial artery
flow-mediated dilation, from 7.7 percent before ingestion
to 8.7 percent four hours after ingestion, as well as
improved digital pulse amplitude tonometry ratio.
However, in the placebo-controlled, cross-over study,
no such changes were observed.
"Additional studies will be needed to determine how
cranberry juice reduces central aortic stiffness, but our
finding of improved pulse wave velocity without a change
in endothelial function may be consistent with an effect
at the level of the arterial wall or a change in sympathetic
tone," the researchers added.
The study was funded by cranberry supplier Ocean
Spray and the National Institutes of Health (NIH).
Source:
American Journal of Clinical Nutrition
(Published online)
"Effects of cranberry juice consumption on vascular
function in patients with coronary artery disease"
Editor's Note: This article is not intended to provide medical advice,
diagnosis or treatment.

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